We have engineered an integration-deficient lentiviral vector, LV305, to deliver the tumor antigen NY-ESO-1 to human dendritic cells in vivo Fragrance through pseudotyping with a modified Sindbis virus envelop protein.Mice immunized once with LV305 developed strong, dose-dependent, multifunctional, and cytotoxic NY-ESO-1-specific cluster of differe
Controlling the sex ratio is essential in finfish farming.A balanced sex ratio is usually good for broodstock management, since it enables to develop appropriate breeding schemes.However, AMAZE CREAM in some species the production of monosex populations is desirable because the existence of sexual dimorphism, primarily in growth or first time of se
Effective planning and optimized execution of the e-Science workflows in distributed systems, such as the Grid, need predictions of execution times of the workflows.However, predicting the execution times of e-Science workflows in heterogeneous distributed systems is a challenging job due to the complex structure of workflows, variations due to inp
While it is well established that the KEAP1-NRF2 pathway regulates the main inducible cellular response to oxidative stress, this cytoprotective function of NRF2 could become deleterious to the host if it confers survival onto irreparably damaged cells.In this regard, we have found that in diseased states, NRF2 promotes the transcriptional activati
Many recent approaches for automated driving (AD) functions currently include components relying on deep neural networks (DNNs).One approach in order to test AD functions is the scenario-based approach.This work formalizes and evaluates the parameter discretization process required in order to yield concrete scenarios for which iPod Wire an AD func